Update on the immunology, diagnosis and management of systemic lupus erythematosus
Identifieur interne : 001F35 ( Main/Exploration ); précédent : 001F34; suivant : 001F36Update on the immunology, diagnosis and management of systemic lupus erythematosus
Auteurs : G. E. M. Reeves [Australie]Source :
- Internal Medicine Journal [ 1444-0903 ] ; 2004-06.
English descriptors
- Teeft :
- Antinuclear, Antinuclear antibodies, Arthritis, Arthritis care, Arthritis rheum, Autoimmune, Autoimmune disease, Autoimmune diseases, Autoimmune disorders, Autoimmunity, Elisa, Erythematosus, Extractable, Fibromyalgia, Immune, Immune response, Immune system, Immunology, Internal medicine journal, John hunter hospital, Lupus, Lupus erythematosus, Major histocompatibility, Pharmacia australia, Rash, Reeves table, Rheumatoid arthritis, Rheumatology, Serological screening, Smith antibody, Syndrome, Syndrome antibody, Systemic, Systemic lupus erythematosus, Test results.
Abstract
Abstract Lupus occurs with a prevalence of 2−9 in 10 000 people, targeting female and indigenous populations in particular. Lupus and related systemic autoimmune syndromes (scleroderma, Sjögren's syndrome, rheumatoid arthritis and polymyositis) result from a similar set of genetically and environmentally modulated immune disturbances, and the diagnostic and management approach to these conditions is broadly comparable. Evanescent , vague symptoms, restrictive diagnostic criteria and low diagnostic suspicion might have resulted in the under‐diagnosis of these problems in the past, imposing considerable burdens on sufferers and the community. Serological screening should be employed cautiously and wisely, given the rapidly occurring changes in methodology, which have lowered their specificity. Close liaison with the immunology laboratories performing these tests is therefore advisable. Clinicians should emphasize the improving prognosis of lupus and related conditions as a result of earlier disease detection, improved educational support systems and refined medical therapies. (Intern Med J 2004: 34: 338−347)
Url:
DOI: 10.1111/j.1444-0903.2004.00578.x
Affiliations:
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E. M." last="Reeves">G. E. M. Reeves</name><affiliation wicri:level="1"><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Immunology and Infectious Diseases, John Hunter Hospital, Newcastle, New South Wales</wicri:regionArea><wicri:noRegion>New South Wales</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Internal Medicine Journal</title><title level="j" type="alt">INTERNAL MEDICINE JOURNAL</title><idno type="ISSN">1444-0903</idno><idno type="eISSN">1445-5994</idno><imprint><biblScope unit="vol">34</biblScope><biblScope unit="issue">6</biblScope><biblScope unit="page" from="338">338</biblScope><biblScope unit="page" to="347">347</biblScope><biblScope unit="page-count">10</biblScope><publisher>Blackwell Science Pty</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2004-06">2004-06</date></imprint><idno type="ISSN">1444-0903</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1444-0903</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Antinuclear</term><term>Antinuclear antibodies</term><term>Arthritis</term><term>Arthritis care</term><term>Arthritis rheum</term><term>Autoimmune</term><term>Autoimmune disease</term><term>Autoimmune diseases</term><term>Autoimmune disorders</term><term>Autoimmunity</term><term>Elisa</term><term>Erythematosus</term><term>Extractable</term><term>Fibromyalgia</term><term>Immune</term><term>Immune response</term><term>Immune system</term><term>Immunology</term><term>Internal medicine journal</term><term>John hunter hospital</term><term>Lupus</term><term>Lupus erythematosus</term><term>Major histocompatibility</term><term>Pharmacia australia</term><term>Rash</term><term>Reeves table</term><term>Rheumatoid arthritis</term><term>Rheumatology</term><term>Serological screening</term><term>Smith antibody</term><term>Syndrome</term><term>Syndrome antibody</term><term>Systemic</term><term>Systemic lupus erythematosus</term><term>Test results</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract Lupus occurs with a prevalence of 2−9 in 10 000 people, targeting female and indigenous populations in particular. Lupus and related systemic autoimmune syndromes (scleroderma, Sjögren's syndrome, rheumatoid arthritis and polymyositis) result from a similar set of genetically and environmentally modulated immune disturbances, and the diagnostic and management approach to these conditions is broadly comparable. Evanescent , vague symptoms, restrictive diagnostic criteria and low diagnostic suspicion might have resulted in the under‐diagnosis of these problems in the past, imposing considerable burdens on sufferers and the community. Serological screening should be employed cautiously and wisely, given the rapidly occurring changes in methodology, which have lowered their specificity. Close liaison with the immunology laboratories performing these tests is therefore advisable. Clinicians should emphasize the improving prognosis of lupus and related conditions as a result of earlier disease detection, improved educational support systems and refined medical therapies. (Intern Med J 2004: 34: 338−347)</div></front></TEI><affiliations><list><country><li>Australie</li></country></list><tree><country name="Australie"><noRegion><name sortKey="Reeves, G E M" sort="Reeves, G E M" uniqKey="Reeves G" first="G. E. M." last="Reeves">G. E. M. Reeves</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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